BAIT
GATA3
HDR, HDRS
GATA binding protein 3
GO Process (58)
GO Function (13)
GO Component (4)
Gene Ontology Biological Process
- T cell receptor signaling pathway [ISS]
- TOR signaling [ISS]
- anatomical structure formation involved in morphogenesis [ISS]
- anatomical structure morphogenesis [TAS]
- aortic valve morphogenesis [ISS]
- blood coagulation [TAS]
- canonical Wnt signaling pathway involved in metanephric kidney development [ISS]
- cardiac right ventricle morphogenesis [ISS]
- cell fate determination [ISS]
- cellular response to interferon-alpha [IEP]
- cellular response to interleukin-4 [IEP]
- cellular response to tumor necrosis factor [IEP]
- defense response [TAS]
- ear development [IMP]
- kidney development [IMP]
- lymphocyte migration [IDA]
- male gonad development [ISS]
- mesenchymal to epithelial transition [IDA]
- mesonephros development [ISS]
- negative regulation of cell cycle [IMP]
- negative regulation of cell motility [IMP]
- negative regulation of cell proliferation [ISS]
- negative regulation of cell proliferation involved in mesonephros development [ISS]
- negative regulation of endothelial cell apoptotic process [IMP]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation [ISS]
- negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation [ISS]
- negative regulation of inflammatory response [IMP]
- negative regulation of mammary gland epithelial cell proliferation [IDA]
- negative regulation of transcription, DNA-templated [IMP]
- nephric duct formation [ISS]
- nephric duct morphogenesis [ISS]
- norepinephrine biosynthetic process [ISS]
- pharyngeal system development [ISS]
- phosphatidylinositol 3-kinase signaling [ISS]
- positive regulation of T cell differentiation [ISS]
- positive regulation of endothelial cell migration [IMP]
- positive regulation of interleukin-13 secretion [IDA, IMP]
- positive regulation of interleukin-4 production [ISS]
- positive regulation of interleukin-5 secretion [IDA]
- positive regulation of protein kinase B signaling [IMP]
- positive regulation of signal transduction [IMP]
- positive regulation of thyroid hormone generation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP, ISS]
- positive regulation of transcription regulatory region DNA binding [IMP]
- positive regulation of transcription, DNA-templated [IDA, IMP, ISS]
- positive regulation of ureteric bud formation [ISS]
- regulation of cellular response to X-ray [IMP]
- regulation of cytokine biosynthetic process [ISS]
- regulation of nephron tubule epithelial cell differentiation [ISS]
- response to estrogen [IEP]
- response to virus [IEP]
- signal transduction [ISS]
- sympathetic nervous system development [ISS]
- transcription from RNA polymerase II promoter [TAS]
- ureteric bud formation [ISS]
- uterus development [ISS]
- ventricular septum development [ISS]
Gene Ontology Molecular Function- DNA binding [TAS]
- E-box binding [IDA]
- HMG box domain binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IMP]
- core promoter proximal region sequence-specific DNA binding [IDA]
- core promoter sequence-specific DNA binding [IDA]
- nucleic acid binding transcription factor activity [IDA, IMP]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [TAS]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
- transcription regulatory region sequence-specific DNA binding [IDA]
- DNA binding [TAS]
- E-box binding [IDA]
- HMG box domain binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IMP]
- core promoter proximal region sequence-specific DNA binding [IDA]
- core promoter sequence-specific DNA binding [IDA]
- nucleic acid binding transcription factor activity [IDA, IMP]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [TAS]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [IDA]
- transcription regulatory region sequence-specific DNA binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
PREY
CYB5R1
B5R.1, B5R1, B5R2, NQO3A2, humb5R2, UNQ3049/PRO9865
cytochrome b5 reductase 1
GO Process (0)
GO Function (0)
GO Component (3)
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A protein interaction landscape of breast cancer.
Cancers have been associated with a diverse array of genomic alterations. To help mechanistically understand such alterations in breast-invasive carcinoma, we applied affinity purification–mass spectrometry to delineate comprehensive biophysical interaction networks for 40 frequently altered breast cancer (BC) proteins, with and without relevant mutations, across three human breast cell lines. These networks identify cancer-specific protein-protein interactions (PPIs), interconnected and enriched ... [more]
Science Oct. 01, 2021; 374(6563);eabf3066 [Pubmed: 34591612]
Throughput
- Low Throughput
Curated By
- BioGRID