BAIT
TBX3
TBX3-ISO, UMS, XHL
T-box 3
GO Process (21)
GO Function (6)
GO Component (1)
Gene Ontology Biological Process
- anterior/posterior axis specification, embryo [IMP]
- cell aging [IDA]
- cellular senescence [IDA]
- embryonic digit morphogenesis [IMP]
- embryonic forelimb morphogenesis [IMP]
- female genitalia development [IMP]
- follicle-stimulating hormone secretion [IMP]
- forelimb morphogenesis [IDA]
- luteinizing hormone secretion [IMP]
- male genitalia development [IMP]
- mammary gland development [IMP]
- mesoderm morphogenesis [IMP]
- negative regulation of apoptotic process [IDA]
- negative regulation of myoblast differentiation [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- organ morphogenesis [IDA]
- positive regulation of cell cycle [IDA]
- positive regulation of cell proliferation [IDA]
- regulation of transcription from RNA polymerase II promoter [TAS]
- skeletal system development [IMP]
Gene Ontology Molecular Function- RNA polymerase II activating transcription factor binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II transcription factor binding [ISS]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- RNA polymerase II activating transcription factor binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II transcription factor binding [ISS]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
Homo sapiens
PREY
ANXA5
ANX5, ENX2, HEL-S-7, PP4, RPRGL3
annexin A5
GO Process (3)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A protein interaction landscape of breast cancer.
Cancers have been associated with a diverse array of genomic alterations. To help mechanistically understand such alterations in breast-invasive carcinoma, we applied affinity purification–mass spectrometry to delineate comprehensive biophysical interaction networks for 40 frequently altered breast cancer (BC) proteins, with and without relevant mutations, across three human breast cell lines. These networks identify cancer-specific protein-protein interactions (PPIs), interconnected and enriched ... [more]
Science Oct. 01, 2021; 374(6563);eabf3066 [Pubmed: 34591612]
Throughput
- Low Throughput
Curated By
- BioGRID