BAIT
KCTD9
BTBD27
potassium channel tetramerization domain containing 9
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
CLTC
CHC, CHC17, CLH-17, CLTCL2, Hc
clathrin, heavy chain (Hc)
GO Process (11)
GO Function (6)
GO Component (15)
Gene Ontology Biological Process
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- intracellular protein transport [NAS]
- membrane organization [TAS]
- mitotic nuclear division [IMP]
- negative regulation of hyaluronan biosynthetic process [IDA, IMP]
- negative regulation of protein localization to plasma membrane [IMP]
- osteoblast differentiation [IDA]
- post-Golgi vesicle-mediated transport [TAS]
- receptor internalization [IMP]
- receptor-mediated endocytosis [IMP]
- transferrin transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- clathrin coat [NAS]
- clathrin complex [IDA]
- clathrin-coated endocytic vesicle membrane [TAS]
- clathrin-coated vesicle [IDA]
- cytoplasm [IDA]
- cytosol [TAS]
- extracellular vesicular exosome [IDA]
- focal adhesion [IDA]
- intracellular membrane-bounded organelle [IDA]
- membrane [IDA]
- plasma membrane [TAS]
- protein complex [IDA]
- spindle [IDA]
- trans-Golgi network membrane [TAS]
- vesicle [IDA]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
KCTD9 inhibits the Wnt/?-catenin pathway by decreasing the level of ?-catenin in colorectal cancer.
Colorectal cancer (CRC) is the second leading cause of cancer mortality worldwide. However, the molecular mechanisms underlying CRC progression remain to be further defined to improve patient outcomes. In this study, we found that KCTD9, a member of the potassium channel tetramerization domain-containing (KCTD) gene family, was commonly downregulated in CRC tissues and that KCTD9 expression was negatively correlated with ... [more]
Cell Death Dis Sep. 02, 2022; 13(9);761 [Pubmed: 36055981]
Throughput
- High Throughput
Curated By
- BioGRID