BAIT

ADIPOR2

ACDCR2, PAQR2
adiponectin receptor 2
GO Process (3)
GO Function (2)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

SLC6A15

NTT73, SBAT1, V7-3, hv7-3
solute carrier family 6 (neutral amino acid transporter), member 15
GO Process (7)
GO Function (1)
GO Component (2)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Regulation of membrane fluidity by RNF145-triggered degradation of the lipid hydrolase ADIPOR2.

Volkmar N, Gawden-Bone CM, Williamson JC, Nixon-Abell J, West JA, St George-Hyslop PH, Kaser A, Lehner PJ

The regulation of membrane lipid composition is critical for cellular homeostasis. Cells are particularly sensitive to phospholipid saturation, with increased saturation causing membrane rigidification and lipotoxicity. How mammalian cells sense membrane lipid composition and reverse fatty acid (FA)-induced membrane rigidification is poorly understood. Here we systematically identify proteins that differ between mammalian cells fed saturated versus unsaturated FAs. The most ... [more]

EMBO J Oct. 04, 2022; 41(19);e110777 [Pubmed: 35993436]

Throughput

  • Low Throughput

Curated By

  • BioGRID