BAIT
GABRA1
ECA4, EIEE19, EJM, EJM5
gamma-aminobutyric acid (GABA) A receptor, alpha 1
GO Process (5)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC25A6
2, 3, AAC3, ANT, ANT 2, ANT 3, ANT3, ANT3Y, RP11-261P4.6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
GO Process (11)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- ADP transport [NAS]
- ATP transport [NAS]
- active induction of host immune response by virus [TAS]
- cellular protein metabolic process [TAS]
- energy reserve metabolic process [TAS]
- modulation by virus of host morphology or physiology [TAS]
- protein targeting to mitochondrion [TAS]
- regulation of insulin secretion [TAS]
- small molecule metabolic process [TAS]
- viral life cycle [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors.
Gamma-aminobutyric acid type A (GABAA) receptors are the primary inhibitory neurotransmitter-gated ion channels in the mammalian central nervous system. Maintenance of GABAA receptor protein homeostasis (proteostasis) in cells utilizing its interacting proteins is essential for the function of GABAA receptors. However, how the proteostasis network orchestrates GABAA receptor biogenesis in the endoplasmic reticulum is not well understood. Here, we employed ... [more]
J Biol Chem Oct. 01, 2022; 298(10);102423 [Pubmed: 36030824]
Throughput
- High Throughput
Curated By
- BioGRID