BIK1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
KIP3
Gene Ontology Biological Process
- establishment of mitotic spindle orientation [IGI, IMP]
- mitotic spindle disassembly [IMP]
- mitotic spindle organization in nucleus [IGI, IMP]
- negative regulation of microtubule polymerization [IMP]
- nuclear migration along microtubule [IMP]
- plus-end specific microtubule depolymerization [IDA]
- regulation of mitotic spindle elongation [IMP]
- spindle assembly involved in mitosis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The microtubule plus-end tracking protein Bik1 is required for chromosome congression.
During mitosis, sister chromatids congress on both sides of the spindle equator to facilitate the correct partitioning of the genomic material. Chromosome congression requires a finely tuned control of microtubule dynamics by the kinesin motor proteins. In Saccharomyces cerevisiae, the kinesin proteins Cin8, Kip1, and Kip3 have a pivotal role in chromosome congression. It has been hypothesized that additional proteins ... [more]
Throughput
- Low Throughput
Additional Notes
- TurboID
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| KIP3 BIK1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1869 | BioGRID | 378756 | |
| BIK1 KIP3 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1869 | BioGRID | 360641 | |
| BIK1 KIP3 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1378 | BioGRID | 2085940 | |
| KIP3 BIK1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.2462 | BioGRID | 2118305 |
Curated By
- BioGRID