BAIT

GABA-B-R2

BcDNA:GH07312, CG6706, D-GABA[[B]]R2, D-Gaba2, Dmel\CG6706, GABA-[[B]]R2, GABABR2, GABA[[B]]-R2, GABA[[B]]R2, GB2, GBR, GH07312, anon-WO0170980.58, anon-WO0170980.59, Dmel_CG6706

metabotropic GABA-B receptor subtype 2

GO Process (6)

GO Function (2)

GO Component (3)

Gene Ontology Biological Process

G-protein coupled receptor signaling pathway [ISS]

gamma-aminobutyric acid signaling pathway [IDA]

negative regulation of adenylate cyclase activity [IDA]

negative regulation of insulin secretion [IMP]

negative regulation of synaptic vesicle fusion to presynaptic membrane [IDA]

olfactory behavior [IDA]

Gene Ontology Molecular Function

G-protein coupled GABA receptor activity [IDA, ISS]
protein heterodimerization activity [IPI]

Gene Ontology Cellular Component

G-protein coupled receptor heterodimeric complex [IPI]

integral component of membrane [ISS]

integral component of plasma membrane [IDA]

CRISPR Database FlyBase Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Drosophila melanogaster

PREY

CG7102

CG17973, Dmel\CG7102, Dmel_CG7102

CG7102 gene product from transcript CG7102-RB

GO Process (0)

GO Function (0)

GO Component (0)

CRISPR Database FlyBase Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Drosophila melanogaster

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

A protein interaction map of Drosophila melanogaster.

Giot L, Bader JS, Brouwer C, Chaudhuri A, Kuang B, Li Y, Hao YL, Ooi CE, Godwin B, Vitols E, Vijayadamodar G, Pochart P, Machineni H, Welsh M, Kong Y, Zerhusen B, Malcolm R, Varrone Z, Collis A, Minto M, Burgess S, McDaniel L, Stimpson E, Spriggs F, Williams J, Neurath K, Ioime N, Agee M, Voss E, Furtak K, Renzulli R, Aanensen N, Carrolla S, Bickelhaupt E, Lazovatsky Y, DaSilva A, Zhong J, Stanyon CA, Finley RL, White KP, Braverman M, Jarvie T, Gold S, Leach M, Knight J, Shimkets RA, McKenna MP, Chant J, Rothberg JM

Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]

Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]

Throughput

High Throughput

Curated By

BioGRID

Interaction Summary