BAIT
CRK
CRKII, p38
v-crk avian sarcoma virus CT10 oncogene homolog
GO Process (11)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- activation of MAPKK activity [TAS]
- blood coagulation [TAS]
- ephrin receptor signaling pathway [IDA]
- innate immune response [TAS]
- insulin receptor signaling pathway [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- platelet activation [TAS]
- regulation of Rho GTPase activity [IDA]
- regulation of actin cytoskeleton organization [IDA]
- regulation of transcription from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
PTPN22
LYP, LYP1, LYP2, PEP, PTPN8
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
GO Process (9)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- T cell differentiation [ISS]
- negative regulation of T cell activation [IMP]
- negative regulation of T cell receptor signaling pathway [IDA]
- peptidyl-tyrosine dephosphorylation [IDA]
- phosphoanandamide dephosphorylation [ISS]
- protein dephosphorylation [IDA, TAS]
- regulation of B cell receptor signaling pathway [NAS]
- regulation of innate immune response [IC]
- regulation of natural killer cell proliferation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.
Specific protein-protein interactions are central to all processes that underlie cell physiology. Numerous studies have together identified hundreds of thousands of human protein-protein interactions. However, many interactions remain to be discovered, and low affinity, conditional, and cell type-specific interactions are likely to be disproportionately underrepresented. Here, we describe an optimized proteomic peptide-phage display library that tiles all disordered regions of ... [more]
Mol Syst Biol Jan. 01, 2022; 18(1);e10584 [Pubmed: 35044719]
Throughput
- High Throughput
Curated By
- BioGRID