BAIT
USP7
HAUSP, TEF1
ubiquitin specific peptidase 7 (herpes virus-associated)
GO Process (8)
GO Function (8)
GO Component (2)
Gene Ontology Biological Process
- histone deubiquitination [IBA]
- maintenance of DNA methylation [IMP]
- negative regulation of NF-kappaB transcription factor activity [IDA]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IBA]
- protein deubiquitination [IDA, IMP]
- regulation of proteasomal protein catabolic process [IBA]
- regulation of sequence-specific DNA binding transcription factor activity [IDA]
- transcription-coupled nucleotide-excision repair [IMP]
Gene Ontology Molecular Function
Homo sapiens
PREY
GRM1
GPRC1A, MGLU1, MGLUR1, PPP1R85, SCAR13
glutamate receptor, metabotropic 1
GO Process (7)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- G-protein coupled glutamate receptor signaling pathway [IBA, IMP]
- G-protein coupled receptor signaling pathway [IDA]
- dimeric G-protein coupled receptor signaling pathway [IDA]
- positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway [IMP]
- protein kinase C-activating G-protein coupled receptor signaling pathway [IBA]
- regulation of synaptic transmission, glutamatergic [IBA]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.
Specific protein-protein interactions are central to all processes that underlie cell physiology. Numerous studies have together identified hundreds of thousands of human protein-protein interactions. However, many interactions remain to be discovered, and low affinity, conditional, and cell type-specific interactions are likely to be disproportionately underrepresented. Here, we describe an optimized proteomic peptide-phage display library that tiles all disordered regions of ... [more]
Mol Syst Biol Jan. 01, 2022; 18(1);e10584 [Pubmed: 35044719]
Throughput
- High Throughput
Curated By
- BioGRID