HDLBP
Gene Ontology Molecular Function
Gene Ontology Cellular Component
TAOK1
Gene Ontology Biological Process
- G2 DNA damage checkpoint [IMP]
- MAPK cascade [IBA]
- activation of MAPKK activity [IBA]
- cellular response to DNA damage stimulus [IDA]
- execution phase of apoptosis [IDA]
- mitotic cell cycle [TAS]
- positive regulation of JNK cascade [IDA]
- positive regulation of stress-activated MAPK cascade [IMP]
- protein phosphorylation [NAS]
- regulation of cytoskeleton organization [ISS]
- spindle checkpoint [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.
The contribution of abnormal metabolic targets to hepatocellular carcinoma (HCC) progression and the associated regulatory mechanisms are attractive research areas. High-density lipoprotein binding protein (HDLBP) is an important transporter that protects cells from excessive cholesterol accumulation, but few studies have identified a role for HDLBP in HCC progression.HDLBP expression was determined in HCC tissues and published datasets. The biological roles ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| HDLBP TAOK1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9867 | BioGRID | 3833733 |
Curated By
- BioGRID