HDLBP
Gene Ontology Molecular Function
Gene Ontology Cellular Component
S100A10
Gene Ontology Biological Process
- establishment of protein localization to plasma membrane [IDA]
- membrane budding [IDA]
- membrane raft assembly [IDA]
- positive regulation of Rac GTPase activity [IMP]
- positive regulation of focal adhesion assembly [IMP]
- positive regulation of stress fiber assembly [IMP]
- positive regulation of substrate adhesion-dependent cell spreading [IMP]
- protein heterotetramerization [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.
The contribution of abnormal metabolic targets to hepatocellular carcinoma (HCC) progression and the associated regulatory mechanisms are attractive research areas. High-density lipoprotein binding protein (HDLBP) is an important transporter that protects cells from excessive cholesterol accumulation, but few studies have identified a role for HDLBP in HCC progression.HDLBP expression was determined in HCC tissues and published datasets. The biological roles ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| S100A10 HDLBP | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.782 | BioGRID | 752333 |
Curated By
- BioGRID