BAIT

HDLBP

HBP, PRO2900, VGL
high density lipoprotein binding protein
GO Process (0)
GO Function (3)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

XRCC6

CTC75, CTCBF, G22P1, KU70, ML8, TLAA, CTA-216E10.7
X-ray repair complementing defective repair in Chinese hamster cells 6
Human Papilloma Virus (HPV) Project
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

Yuan J, Lv T, Yang J, Wu Z, Yan L, Yang J, Shi Y, Jiang L

The contribution of abnormal metabolic targets to hepatocellular carcinoma (HCC) progression and the associated regulatory mechanisms are attractive research areas. High-density lipoprotein binding protein (HDLBP) is an important transporter that protects cells from excessive cholesterol accumulation, but few studies have identified a role for HDLBP in HCC progression.HDLBP expression was determined in HCC tissues and published datasets. The biological roles ... [more]

Cell Mol Gastroenterol Hepatol Oct. 17, 2022; 15(2);307-325 [Pubmed: 36244648]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
XRCC6 HDLBP
Co-fractionation
Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

High-BioGRID
3437883

Curated By

  • BioGRID