BAIT
HDLBP
HBP, PRO2900, VGL
high density lipoprotein binding protein
GO Process (0)
GO Function (3)
GO Component (2)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SNX33
SH3PX3, SH3PXD3C, SNX30
sorting nexin 33
GO Process (13)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- cleavage furrow formation [IMP]
- endocytosis [IMP]
- endosomal transport [IMP]
- endosome organization [IMP]
- macropinocytosis [IMP]
- membrane tubulation [IDA]
- mitotic cytokinesis [IMP]
- negative regulation of endocytosis [IDA]
- negative regulation of protein localization to cell surface [IDA]
- positive regulation of membrane protein ectodomain proteolysis [IDA]
- positive regulation of protein localization to cell surface [IDA]
- protein import [IDA]
- vesicle organization [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.
The contribution of abnormal metabolic targets to hepatocellular carcinoma (HCC) progression and the associated regulatory mechanisms are attractive research areas. High-density lipoprotein binding protein (HDLBP) is an important transporter that protects cells from excessive cholesterol accumulation, but few studies have identified a role for HDLBP in HCC progression.HDLBP expression was determined in HCC tissues and published datasets. The biological roles ... [more]
Cell Mol Gastroenterol Hepatol Oct. 17, 2022; 15(2);307-325 [Pubmed: 36244648]
Throughput
- Low Throughput
Curated By
- BioGRID