CDC36
Gene Ontology Biological Process
- deadenylation-independent decapping of nuclear-transcribed mRNA [IMP]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [IDA, IGI, IMP]
- nuclear-transcribed mRNA poly(A) tail shortening [IDA]
- positive regulation of transcription elongation from RNA polymerase II promoter [IDA, IPI]
- protein ubiquitination [IMP]
- regulation of cell cycle [IMP]
- regulation of transcription from RNA polymerase II promoter [IPI]
- response to pheromone involved in conjugation with cellular fusion [IMP]
- transcription elongation from RNA polymerase II promoter [IMP]
Gene Ontology Molecular Function
SKI6
Gene Ontology Biological Process
- U1 snRNA 3'-end processing [IGI, IMP]
- U4 snRNA 3'-end processing [IGI, IMP]
- U5 snRNA 3'-end processing [IGI, IMP]
- exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IMP]
- nonfunctional rRNA decay [IC]
- nuclear mRNA surveillance [IGI, IMP]
- nuclear polyadenylation-dependent CUT catabolic process [IMP]
- nuclear polyadenylation-dependent mRNA catabolic process [IC]
- nuclear polyadenylation-dependent tRNA catabolic process [IDA]
- nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [IGI, IMP]
- nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [IMP]
- nuclear-transcribed mRNA catabolic process, non-stop decay [IC]
- polyadenylation-dependent snoRNA 3'-end processing [IMP]
- rRNA catabolic process [IMP]
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The CCR4-NOT complex physically and functionally interacts with TRAMP and the nuclear exosome.
BACKGROUND: Ccr4-Not is a highly conserved multi-protein complex consisting in yeast of 9 subunits, including Not5 and the major yeast deadenylase Ccr4. It has been connected functionally in the nucleus to transcription by RNA polymerase II and in the cytoplasm to mRNA degradation. However, there has been no evidence so far that this complex is important for RNA degradation in ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID