BAIT
MICALL2
JRAB, MICAL-L2, UNQ5811
MICAL-like 2
GO Process (6)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
STOML2
SLP-2, HSPC108
stomatin (EPB72)-like 2
GO Process (14)
GO Function (3)
GO Component (9)
Gene Ontology Biological Process
- CD4-positive, alpha-beta T cell activation [ISS]
- T cell receptor signaling pathway [IMP]
- cellular calcium ion homeostasis [IMP]
- interleukin-2 production [ISS]
- lipid localization [ISS]
- mitochondrial ATP synthesis coupled proton transport [IMP]
- mitochondrial calcium ion transport [IMP]
- mitochondrial protein processing [ISS]
- mitochondrion organization [IMP]
- positive regulation of cardiolipin metabolic process [IMP]
- positive regulation of mitochondrial DNA replication [IMP]
- positive regulation of mitochondrial membrane potential [IMP]
- protein oligomerization [IDA]
- stress-induced mitochondrial fusion [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.
Molecule interacting with CasL-like protein 2 (MICALL2) is believed to regulate cytoskeleton dynamics, tight junction formation, and neurite outgrowth. However, its biological role and the underlying mechanism in colorectal cancer (CRC) remain largely elusive.qRT-PCR, Western blotting and immunohistochemistry assays were used to detect the expression levels of different genes. Next, mass spectrometry, co-immunoprecipitation and immunofluorescence staining were used to detect ... [more]
Cell Commun Signal Oct. 28, 2022; 20(1);170 [Pubmed: 36307841]
Throughput
- High Throughput
Curated By
- BioGRID