BAIT
MICALL2
JRAB, MICAL-L2, UNQ5811
MICAL-like 2
GO Process (6)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PYCR1
ARCL2B, ARCL3B, P5C, P5CR, PIG45, PP222, PRO3, PYCR
pyrroline-5-carboxylate reductase 1
GO Process (7)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- cellular amino acid biosynthetic process [TAS]
- cellular nitrogen compound metabolic process [TAS]
- cellular response to oxidative stress [IMP]
- negative regulation of hydrogen peroxide-induced cell death [IMP]
- proline biosynthetic process [IDA]
- regulation of mitochondrial membrane potential [IMP]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.
Molecule interacting with CasL-like protein 2 (MICALL2) is believed to regulate cytoskeleton dynamics, tight junction formation, and neurite outgrowth. However, its biological role and the underlying mechanism in colorectal cancer (CRC) remain largely elusive.qRT-PCR, Western blotting and immunohistochemistry assays were used to detect the expression levels of different genes. Next, mass spectrometry, co-immunoprecipitation and immunofluorescence staining were used to detect ... [more]
Cell Commun Signal Oct. 28, 2022; 20(1);170 [Pubmed: 36307841]
Throughput
- High Throughput
Curated By
- BioGRID