BAIT
TRIM67
TNL
tripartite motif containing 67
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
OGT
HRNT1, O-GLCNAC
O-linked N-acetylglucosamine (GlcNAc) transferase
GO Process (24)
GO Function (9)
GO Component (8)
Gene Ontology Biological Process
- apoptotic process [IDA]
- cellular response to retinoic acid [IMP]
- chromatin organization [TAS]
- circadian regulation of gene expression [ISS]
- histone H3-K4 trimethylation [IMP]
- histone H4-K16 acetylation [IDA]
- histone H4-K5 acetylation [IDA]
- histone H4-K8 acetylation [IDA]
- negative regulation of protein ubiquitination [ISS]
- phosphatidylinositol-mediated signaling [IDA]
- positive regulation of catalytic activity [IDA]
- positive regulation of granulocyte differentiation [IMP]
- positive regulation of histone H3-K27 methylation [IMP]
- positive regulation of histone H3-K4 methylation [IDA]
- positive regulation of proteolysis [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- protein O-linked glycosylation [IDA, IMP]
- regulation of Rac protein signal transduction [IDA]
- regulation of gluconeogenesis involved in cellular glucose homeostasis [ISS]
- regulation of glycolytic process [IDA]
- regulation of insulin receptor signaling pathway [IDA]
- response to insulin [IDA]
- response to nutrient [TAS]
- signal transduction [TAS]
Gene Ontology Molecular Function- acetylglucosaminyltransferase activity [TAS]
- enzyme activator activity [IDA]
- histone acetyltransferase activity (H4-K16 specific) [IDA]
- histone acetyltransferase activity (H4-K5 specific) [IDA]
- histone acetyltransferase activity (H4-K8 specific) [IDA]
- phosphatidylinositol-3,4,5-trisphosphate binding [IDA]
- protein N-acetylglucosaminyltransferase activity [IDA]
- protein O-GlcNAc transferase activity [IMP, ISS]
- protein binding [IPI]
- acetylglucosaminyltransferase activity [TAS]
- enzyme activator activity [IDA]
- histone acetyltransferase activity (H4-K16 specific) [IDA]
- histone acetyltransferase activity (H4-K5 specific) [IDA]
- histone acetyltransferase activity (H4-K8 specific) [IDA]
- phosphatidylinositol-3,4,5-trisphosphate binding [IDA]
- protein N-acetylglucosaminyltransferase activity [IDA]
- protein O-GlcNAc transferase activity [IMP, ISS]
- protein binding [IPI]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing.
IDH mutant gliomas are grouped into astrocytomas or oligodendrogliomas depending on the co-deletion of chromosome arms 1p and 19q. Although the genomic alterations of IDH mutant gliomas have been well described, transcriptional changes unique to either tumor type have not been fully understood. Here, we identify Tripartite Motif Containing 67 (TRIM67), an E3 ubiquitin ligase with essential roles during neuronal ... [more]
Neuro Oncol Oct. 10, 2022; (); [Pubmed: 36215168]
Throughput
- High Throughput|Low Throughput
Curated By
- BioGRID