BAIT

RPN2

RIBIIR, RPN-II, RPNII, SWP1, RP3-343K2.2

ribophorin II

GO Process (7)

GO Function (1)

GO Component (5)

Gene Ontology Biological Process

SRP-dependent cotranslational protein targeting to membrane [TAS]

cellular protein metabolic process [TAS]

cellular protein modification process [TAS]

gene expression [TAS]

post-translational protein modification [TAS]

protein N-linked glycosylation via asparagine [NAS, TAS]

translation [TAS]

Gene Ontology Molecular Function

dolichyl-diphosphooligosaccharide-protein glycotransferase activity [NAS]

Gene Ontology Cellular Component

endoplasmic reticulum [IDA]

endoplasmic reticulum membrane [TAS]

oligosaccharyltransferase complex [TAS]

CRISPR Database OMIM VEGA HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

FIS1

TTC11, CGI-135

fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)

GO Process (18)

GO Function (2)

GO Component (6)

Gene Ontology Biological Process

calcium-mediated signaling using intracellular calcium source [IMP]

mitochondrial fission [IDA, IMP]

mitochondrial fragmentation involved in apoptotic process [IDA, IMP]

mitochondrial fusion [IMP]

mitochondrion degradation [IDA]

mitochondrion morphogenesis [IMP]

negative regulation of endoplasmic reticulum calcium ion concentration [IMP]

peroxisome fission [IDA, IMP]

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]

positive regulation of cytosolic calcium ion concentration [IMP]

positive regulation of intrinsic apoptotic signaling pathway [IMP]

positive regulation of mitochondrial calcium ion concentration [IMP]

positive regulation of mitochondrial fission [IDA]

positive regulation of protein targeting to membrane [IDA]

protein homooligomerization [IMP]

protein targeting to mitochondrion [IMP]

regulation of mitochondrion organization [IMP]

release of cytochrome c from mitochondria [IMP]

Gene Ontology Molecular Function

protein binding [IPI]
receptor binding [IPI]

Gene Ontology Cellular Component

integral component of mitochondrial outer membrane [IDA, NAS]

integral component of peroxisomal membrane [IDA]

mitochondrion [IDA]

peroxisome [IDA, ISS]

protein complex [IDA]

CRISPR Database HGNC Alliance of Genome Resources OMIM VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.

Li B, Zhao R, Qiu W, Pan Z, Zhao S, Qi Y, Qiu J, Zhang S, Guo Q, Fan Y, Xu H, Li M, Li G, Xue H

Background: Glioblastoma (GBM) is the most common primary brain malignancy and has high aggressiveness and a poor prognosis. N6-methyladenosine (m6A) represents the most prevalent methylation modification of lncRNAs and has been shown to play important roles in the pathophysiological processes of tumors. However, the distribution and function of m6A modifications in lncRNAs in GBM tissues have not been fully revealed. ... [more]

Theranostics Sep. 29, 2022; 12(14);6363-6379 [Pubmed: 36168628]

Throughput

High Throughput

Curated By

BioGRID