BAIT

RPN2

RIBIIR, RPN-II, RPNII, SWP1, RP3-343K2.2

ribophorin II

GO Process (7)

GO Function (1)

GO Component (5)

Gene Ontology Biological Process

SRP-dependent cotranslational protein targeting to membrane [TAS]

cellular protein metabolic process [TAS]

cellular protein modification process [TAS]

gene expression [TAS]

post-translational protein modification [TAS]

protein N-linked glycosylation via asparagine [NAS, TAS]

translation [TAS]

Gene Ontology Molecular Function

dolichyl-diphosphooligosaccharide-protein glycotransferase activity [NAS]

Gene Ontology Cellular Component

endoplasmic reticulum [IDA]

endoplasmic reticulum membrane [TAS]

oligosaccharyltransferase complex [TAS]

CRISPR Database OMIM VEGA HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

LSM2

C6orf28, G7B, YBL026W, snRNP, DAAP-21F2.6

LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)

GO Process (7)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

RNA metabolic process [TAS]

RNA splicing [TAS]

exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay [TAS]

gene expression [TAS]

mRNA metabolic process [TAS]

mRNA splicing, via spliceosome [IC, TAS]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]

Gene Ontology Molecular Function

U6 snRNA binding [NAS]
poly(A) RNA binding [IDA]
protein binding [IPI]

Gene Ontology Cellular Component

catalytic step 2 spliceosome [IDA]

nucleoplasm [IDA, TAS]

CRISPR Database VEGA OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.

Li B, Zhao R, Qiu W, Pan Z, Zhao S, Qi Y, Qiu J, Zhang S, Guo Q, Fan Y, Xu H, Li M, Li G, Xue H

Background: Glioblastoma (GBM) is the most common primary brain malignancy and has high aggressiveness and a poor prognosis. N6-methyladenosine (m6A) represents the most prevalent methylation modification of lncRNAs and has been shown to play important roles in the pathophysiological processes of tumors. However, the distribution and function of m6A modifications in lncRNAs in GBM tissues have not been fully revealed. ... [more]

Theranostics Sep. 29, 2022; 12(14);6363-6379 [Pubmed: 36168628]

Throughput

High Throughput

Curated By

BioGRID