BAIT
TRIM67
TNL
tripartite motif containing 67
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
SLC8A1
NCX1
solute carrier family 8 (sodium/calcium exchanger), member 1
GO Process (29)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- blood coagulation [TAS]
- calcium ion export [IDA]
- calcium ion homeostasis [ISS]
- calcium ion import [IDA]
- calcium ion transport into cytosol [ISS]
- cardiac muscle cell development [ISS]
- cardiac muscle contraction [TAS]
- cell communication by electrical coupling involved in cardiac conduction [ISS]
- cellular response to caffeine [ISS]
- cellular response to reactive oxygen species [IDA]
- cellular sodium ion homeostasis [IDA]
- cytosolic calcium ion transport [TAS]
- ion transport [TAS]
- membrane depolarization during cardiac muscle cell action potential [TAS]
- muscle contraction [TAS]
- negative regulation of cytosolic calcium ion concentration [ISS]
- positive regulation of the force of heart contraction [IMP]
- regulation of cardiac muscle contraction by calcium ion signaling [TAS]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [ISS, TAS]
- regulation of cell communication by electrical coupling [TAS]
- regulation of heart rate [ISS]
- regulation of the force of heart contraction [IC, ISS]
- relaxation of cardiac muscle [IC, TAS]
- relaxation of smooth muscle [ISS]
- response to muscle stretch [IMP]
- sodium ion export [IDA]
- sodium ion import [IDA]
- transmembrane transport [TAS]
- vascular smooth muscle contraction [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing.
IDH mutant gliomas are grouped into astrocytomas or oligodendrogliomas depending on the co-deletion of chromosome arms 1p and 19q. Although the genomic alterations of IDH mutant gliomas have been well described, transcriptional changes unique to either tumor type have not been fully understood. Here, we identify Tripartite Motif Containing 67 (TRIM67), an E3 ubiquitin ligase with essential roles during neuronal ... [more]
Neuro Oncol Oct. 10, 2022; (); [Pubmed: 36215168]
Throughput
- High Throughput
Curated By
- BioGRID