BAIT

TRIM67

TNL
tripartite motif containing 67
UPS Project
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

RBX1

BA554C12.1, RNF75, ROC1, RP11-554C12.1
ring-box 1, E3 ubiquitin protein ligase
UPS Project
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing.

Demirdizen E, Al-Ali R, Narayanan A, Sun X, Varga JP, Steffl B, Brom M, Krunic D, Schmidt C, Schmidt G, Bestvater F, Taranda J, Turcan S

IDH mutant gliomas are grouped into astrocytomas or oligodendrogliomas depending on the co-deletion of chromosome arms 1p and 19q. Although the genomic alterations of IDH mutant gliomas have been well described, transcriptional changes unique to either tumor type have not been fully understood. Here, we identify Tripartite Motif Containing 67 (TRIM67), an E3 ubiquitin ligase with essential roles during neuronal ... [more]

Neuro Oncol Oct. 10, 2022; (); [Pubmed: 36215168]

Throughput

  • High Throughput

Curated By

  • BioGRID