MYO2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RNG2
Gene Ontology Biological Process
- actin filament bundle assembly [IDA]
- actomyosin contractile ring actin filament bundle assembly [IDA]
- actomyosin contractile ring assembly actin filament bundle convergence [IDA]
- mitotic actomyosin contractile ring assembly [IMP]
- mitotic actomyosin contractile ring assembly actin filament organization [IMP]
- mitotic actomyosin contractile ring localization [IMP]
- mitotic cytokinesis [IMP]
- protein localization to medial cortex [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Genome-wide mapping of myosin protein-RNA networks suggests the existence of specialized protein production sites.
Motor proteins can organize posttranscriptional processes by transporting ribonucleoprotein complexes to specific locations. To investigate a possible role of myosin proteins in gene expression control, I have identified mRNAs associated with five myosin heavy chains in the fission yeast Schizosaccharomyces pombe, by purifying the proteins and identifying bound transcripts using DNA microarrays. Each myosin coimmunoprecipitated with 5-13 different mRNAs (approximately ... [more]
Throughput
- Low Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
RNG2 MYO2 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - | |
RNG2 MYO2 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 300738 |
Curated By
- BioGRID