BAIT
TRIM67
TNL
tripartite motif containing 67
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
NRP1
BDCA4, CD304, NP1, NRP, VEGF165R, RP11-342D11.1
neuropilin 1
GO Process (43)
GO Function (7)
GO Component (10)
Gene Ontology Biological Process
- VEGF-activated neuropilin signaling pathway [ISS]
- angiogenesis [IMP, ISS]
- angiogenesis involved in coronary vascular morphogenesis [ISS]
- artery morphogenesis [ISS]
- axon extension involved in axon guidance [ISS]
- axon guidance [NAS, TAS]
- axonogenesis involved in innervation [ISS]
- cell migration involved in sprouting angiogenesis [ISS]
- cell-cell signaling [TAS]
- cellular response to hepatocyte growth factor stimulus [IMP]
- cellular response to vascular endothelial growth factor stimulus [ISS]
- commissural neuron axon guidance [ISS]
- endothelial cell chemotaxis [IMP]
- endothelial tip cell fate specification [ISS]
- hepatocyte growth factor receptor signaling pathway [IMP]
- nerve development [ISS]
- neural crest cell migration involved in autonomic nervous system development [ISS]
- neuron migration [ISS]
- organ morphogenesis [TAS]
- patterning of blood vessels [ISS]
- platelet-derived growth factor receptor signaling pathway [IMP]
- positive chemotaxis [ISS]
- positive regulation of ERK1 and ERK2 cascade [ISS]
- positive regulation of axon extension involved in axon guidance [ISS]
- positive regulation of cytokine activity [TAS]
- positive regulation of endothelial cell migration [TAS]
- positive regulation of endothelial cell proliferation [TAS]
- positive regulation of peptidyl-tyrosine phosphorylation [IMP]
- positive regulation of retinal ganglion cell axon guidance [ISS]
- positive regulation of smooth muscle cell migration [TAS]
- protein localization to early endosome [ISS]
- regulation of retinal ganglion cell axon guidance [ISS]
- regulation of vesicle-mediated transport [TAS]
- retina vasculature morphogenesis in camera-type eye [ISS]
- retinal ganglion cell axon guidance [ISS]
- semaphorin-plexin signaling pathway [NAS]
- semaphorin-plexin signaling pathway involved in neuron projection guidance [ISS]
- signal transduction [TAS]
- sprouting angiogenesis [ISS]
- sympathetic ganglion development [ISS]
- sympathetic neuron projection extension [ISS]
- sympathetic neuron projection guidance [ISS]
- vascular endothelial growth factor receptor signaling pathway [IMP, TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing.
IDH mutant gliomas are grouped into astrocytomas or oligodendrogliomas depending on the co-deletion of chromosome arms 1p and 19q. Although the genomic alterations of IDH mutant gliomas have been well described, transcriptional changes unique to either tumor type have not been fully understood. Here, we identify Tripartite Motif Containing 67 (TRIM67), an E3 ubiquitin ligase with essential roles during neuronal ... [more]
Neuro Oncol Oct. 10, 2022; (); [Pubmed: 36215168]
Throughput
- High Throughput
Curated By
- BioGRID