BAIT
USP48
2810449C13Rik, AI115503, BC021769, D330022K21Rik, Usp31, RP23-277N22.2
ubiquitin specific peptidase 48
GO Process (3)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ACTR3
1200003A09Rik, Arp3
ARP3 actin-related protein 3
GO Process (14)
GO Function (3)
GO Component (14)
Gene Ontology Biological Process
- Arp2/3 complex-mediated actin nucleation [ISO]
- asymmetric cell division [IGI]
- cilium morphogenesis [ISO]
- establishment or maintenance of cell polarity [IGI]
- meiotic cell cycle [IGI]
- meiotic chromosome movement towards spindle pole [IGI]
- meiotic cytokinesis [IGI]
- positive regulation of actin filament polymerization [ISO]
- positive regulation of dendrite morphogenesis [ISO]
- positive regulation of filopodium assembly [ISO]
- positive regulation of lamellipodium assembly [ISO]
- positive regulation of neuron differentiation [ISO]
- regulation of myosin II filament organization [ISO]
- spindle localization [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.
Proteins related to the ubiquitin-proteasome system play an important role during the differentiation and ciliogenesis of photoreceptor cells. Mutations in several genes involved in ubiquitination and proteostasis have been identified as causative of inherited retinal dystrophies (IRDs) and ciliopathies. USP48 is a deubiquitinating enzyme whose role in the retina is still unexplored although previous studies indicate its relevance for neurosensory ... [more]
Int J Mol Sci Oct. 19, 2022; 23(20); [Pubmed: 36293380]
Throughput
- High Throughput
Curated By
- BioGRID