BAIT
USP48
2810449C13Rik, AI115503, BC021769, D330022K21Rik, Usp31, RP23-277N22.2
ubiquitin specific peptidase 48
GO Process (3)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
G6PDX
G28A, G6pd, Gpdx, RP23-436K3.17-003
glucose-6-phosphate dehydrogenase X-linked
GO Process (24)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
- NADP biosynthetic process [IDA, IMP]
- NADP metabolic process [ISO]
- NADPH regeneration [ISO]
- angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure [IMP]
- cellular response to oxidative stress [ISO]
- cholesterol biosynthetic process [ISO]
- cytokine production [IMP, ISO]
- erythrocyte development [IMP]
- erythrocyte maturation [ISO]
- glucose 6-phosphate metabolic process [ISO]
- glutathione metabolic process [IMP, ISO]
- interleukin-10 production [IMP]
- interleukin-12 production [IMP]
- negative regulation of protein glutathionylation [ISO]
- oxidation-reduction process [IMP, ISO]
- pentose biosynthetic process [IDA, IMP, ISO]
- pentose-phosphate shunt [ISO]
- pentose-phosphate shunt, oxidative branch [ISO]
- regulation of multicellular organism growth [IMP]
- regulation of neuron apoptotic process [ISO]
- response to ethanol [ISO]
- response to oxidative stress [IMP]
- ribose phosphate biosynthetic process [ISO]
- vasodilation by angiotensin involved in regulation of systemic arterial blood pressure [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.
Proteins related to the ubiquitin-proteasome system play an important role during the differentiation and ciliogenesis of photoreceptor cells. Mutations in several genes involved in ubiquitination and proteostasis have been identified as causative of inherited retinal dystrophies (IRDs) and ciliopathies. USP48 is a deubiquitinating enzyme whose role in the retina is still unexplored although previous studies indicate its relevance for neurosensory ... [more]
Int J Mol Sci Oct. 19, 2022; 23(20); [Pubmed: 36293380]
Throughput
- High Throughput
Curated By
- BioGRID