BAIT
USP48
2810449C13Rik, AI115503, BC021769, D330022K21Rik, Usp31, RP23-277N22.2
ubiquitin specific peptidase 48
GO Process (3)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
GNAT2
AW490837, Gnat-2, Gt-2, Tcalpha, RP23-89M15.3
guanine nucleotide binding protein, alpha transducing 2
GO Process (12)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [ISO]
- G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [TAS]
- GTP catabolic process [IBA]
- adenylate cyclase-modulating G-protein coupled receptor signaling pathway [IBA]
- detection of chemical stimulus involved in sensory perception of bitter taste [IBA, ISO]
- detection of light stimulus involved in visual perception [IMP, ISO]
- detection of visible light [IBA]
- phototransduction [IMP, TAS]
- positive regulation of cytosolic calcium ion concentration [ISO]
- response to light intensity [ISO]
- retinal cone cell development [IMP]
- visual perception [IMP, TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.
Proteins related to the ubiquitin-proteasome system play an important role during the differentiation and ciliogenesis of photoreceptor cells. Mutations in several genes involved in ubiquitination and proteostasis have been identified as causative of inherited retinal dystrophies (IRDs) and ciliopathies. USP48 is a deubiquitinating enzyme whose role in the retina is still unexplored although previous studies indicate its relevance for neurosensory ... [more]
Int J Mol Sci Oct. 19, 2022; 23(20); [Pubmed: 36293380]
Throughput
- High Throughput
Curated By
- BioGRID