BAIT
USP48
2810449C13Rik, AI115503, BC021769, D330022K21Rik, Usp31, RP23-277N22.2
ubiquitin specific peptidase 48
GO Process (3)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
STX3
Syn-3
syntaxin 3
GO Process (12)
GO Function (4)
GO Component (16)
Gene Ontology Biological Process
- exocytosis [IMP]
- intracellular protein transport [IBA]
- long-term synaptic potentiation [IMP]
- membrane fusion [ISO]
- neuron projection development [ISO]
- positive regulation of cell adhesion [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of chemotaxis [ISO]
- positive regulation of protein localization to cell surface [ISO]
- positive regulation of protein localization to plasma membrane [ISO]
- synaptic vesicle fusion to presynaptic membrane [IBA]
- vesicle docking [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- SNARE complex [IBA, ISO]
- apical plasma membrane [IDA, ISO]
- azurophil granule [ISO]
- cell [IMP]
- cell-cell junction [ISO]
- dendrite [IDA]
- extracellular vesicular exosome [ISO]
- growth cone [ISO]
- integral component of membrane [IBA]
- lamellipodium [ISO]
- membrane [IDA]
- neuron projection [ISO]
- plasma membrane [ISO]
- secretory granule [IDA]
- specific granule [ISO]
- synaptic vesicle [IBA]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.
Proteins related to the ubiquitin-proteasome system play an important role during the differentiation and ciliogenesis of photoreceptor cells. Mutations in several genes involved in ubiquitination and proteostasis have been identified as causative of inherited retinal dystrophies (IRDs) and ciliopathies. USP48 is a deubiquitinating enzyme whose role in the retina is still unexplored although previous studies indicate its relevance for neurosensory ... [more]
Int J Mol Sci Oct. 19, 2022; 23(20); [Pubmed: 36293380]
Throughput
- High Throughput
Curated By
- BioGRID