BAIT
USP48
2810449C13Rik, AI115503, BC021769, D330022K21Rik, Usp31, RP23-277N22.2
ubiquitin specific peptidase 48
GO Process (3)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RAB1
Gtbp, Rab-1, Rab1A, Ypt1, mKIAA3012, RP23-19L22.4
RAB1, member RAS oncogene family
GO Process (18)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- ER to Golgi vesicle-mediated transport [IBA, ISA, ISO]
- GTP catabolic process [IBA, ISO]
- Golgi organization [ISO]
- Rab protein signal transduction [IBA]
- autophagic vacuole assembly [IBA, ISO]
- autophagy [ISO]
- cargo loading into COPII-coated vesicle [ISO]
- cell migration [IMP, ISO]
- defense response to bacterium [ISO]
- endocytosis [ISO]
- growth hormone secretion [ISO]
- interleukin-8 secretion [ISO]
- intracellular protein transport [TAS]
- melanosome transport [IMP]
- positive regulation of glycoprotein metabolic process [ISO]
- substrate adhesion-dependent cell spreading [IMP]
- vesicle transport along microtubule [ISO]
- virion assembly [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.
Proteins related to the ubiquitin-proteasome system play an important role during the differentiation and ciliogenesis of photoreceptor cells. Mutations in several genes involved in ubiquitination and proteostasis have been identified as causative of inherited retinal dystrophies (IRDs) and ciliopathies. USP48 is a deubiquitinating enzyme whose role in the retina is still unexplored although previous studies indicate its relevance for neurosensory ... [more]
Int J Mol Sci Oct. 19, 2022; 23(20); [Pubmed: 36293380]
Throughput
- High Throughput
Curated By
- BioGRID