BAIT
USP48
2810449C13Rik, AI115503, BC021769, D330022K21Rik, Usp31, RP23-277N22.2
ubiquitin specific peptidase 48
GO Process (3)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
GLUL
GS, Glns
glutamate-ammonia ligase (glutamine synthetase)
GO Process (10)
GO Function (8)
GO Component (14)
Gene Ontology Biological Process
- ammonia assimilation cycle [ISO]
- cell proliferation [ISO]
- cellular response to starvation [IEP]
- glutamate metabolic process [ISO]
- glutamine biosynthetic process [ISO]
- positive regulation of epithelial cell proliferation [ISO]
- positive regulation of insulin secretion [ISO]
- positive regulation of synaptic transmission, glutamatergic [ISO]
- protein homooligomerization [ISO]
- response to glucose [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon terminus [ISO]
- cell body [IDA]
- cell projection [ISO]
- cytoplasm [IDA, ISO]
- extracellular vesicular exosome [ISO]
- glial cell projection [IDA]
- intracellular membrane-bounded organelle [ISO]
- mitochondrion [IDA]
- myelin sheath [IDA]
- neuron projection [ISO]
- nucleus [ISO]
- perikaryon [ISO]
- protein complex [ISO]
- rough endoplasmic reticulum [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.
Proteins related to the ubiquitin-proteasome system play an important role during the differentiation and ciliogenesis of photoreceptor cells. Mutations in several genes involved in ubiquitination and proteostasis have been identified as causative of inherited retinal dystrophies (IRDs) and ciliopathies. USP48 is a deubiquitinating enzyme whose role in the retina is still unexplored although previous studies indicate its relevance for neurosensory ... [more]
Int J Mol Sci Oct. 19, 2022; 23(20); [Pubmed: 36293380]
Throughput
- High Throughput
Curated By
- BioGRID