STAU1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RBM4
Gene Ontology Biological Process
- IRES-dependent translational initiation [IDA]
- RNA processing [TAS]
- cap-independent translational initiation [IDA]
- circadian regulation of translation [ISS]
- entrainment of circadian clock by photoperiod [ISS]
- negative regulation of translation [IDA]
- negative regulation of translation in response to stress [IDA]
- negative regulation of translation involved in gene silencing by miRNA [IDA]
- negative regulation of translational initiation [IDA]
- positive regulation of muscle cell differentiation [IDA]
- regulation of alternative mRNA splicing, via spliceosome [IDA]
- regulation of nucleocytoplasmic transport [IDA]
- response to arsenic-containing substance [IDA]
- stress-activated MAPK cascade [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.
Cancer development is regulated by inflammation. Staufen1 (STAU1) is an RNA-binding protein whose expression level is critical in cancer cells as it is related to cell proliferation or cell death. STAU1 protein levels are downregulated during mitosis due to its degradation by the E3 ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C). In this paper, we map the molecular determinant involved in STAU1 ... [more]
Throughput
- High Throughput
Additional Notes
- Proximity label-MS was carried out to identify high confidence protein interactors with a total spectrum count of greater than or equal to four times over control
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| STAU1 RBM4 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID