BAIT
ASXL3
BRPS, KIAA1713
additional sex combs like transcriptional regulator 3
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
GSTM2
GST4, GSTM, GSTM2-2, GTHMUS
glutathione S-transferase mu 2 (muscle)
GO Process (14)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- cellular detoxification of nitrogen compound [IDA]
- cellular response to caffeine [IDA]
- glutathione derivative biosynthetic process [TAS]
- glutathione metabolic process [IDA]
- negative regulation of ryanodine-sensitive calcium-release channel activity [IDA]
- nitrobenzene metabolic process [IDA]
- positive regulation of ryanodine-sensitive calcium-release channel activity [IDA]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [IC]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [IDA]
- regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [IC]
- relaxation of cardiac muscle [TAS]
- small molecule metabolic process [TAS]
- xenobiotic catabolic process [IDA]
- xenobiotic metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer.
BRCA1-associated protein 1 (BAP1) is an ubiquitin carboxy-terminal hydrolase, which forms a multi-protein complex with different epigenetic factors, such as ASXL1-3 and FOXK1/2. At the chromatin level, BAP1 catalyzes the removal of mono-ubiquitination on histone H2AK119 in collaboration with other subunits within the complex and functions as a transcriptional activator in mammalian cells. However, the crosstalk between different subunits and ... [more]
Genome Biol Sep. 30, 2022; 23(1);206 [Pubmed: 36180891]
Throughput
- Low Throughput
Curated By
- BioGRID