BAIT
LINC00624
RP11-441L11.1
long intergenic non-protein coding RNA 624
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
SFPQ
POMP100, PPP1R140, PSF
splicing factor proline/glutamine-rich
GO Process (9)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- RNA splicing [TAS]
- alternative mRNA splicing, via spliceosome [IMP]
- histone H3 deacetylation [ISS]
- mRNA processing [TAS]
- negative regulation of circadian rhythm [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP]
- negative regulation of transcription, DNA-templated [ISS]
- positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [IDA]
- regulation of circadian rhythm [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
Immunosuppressive lncRNA LINC00624 promotes tumor progression and therapy resistance through ADAR1 stabilization.
Despite the success of HER2-targeted therapy in achieving prolonged survival in approximately 50% of treated individuals, treatment resistance is still an important challenge for HER2+ breast cancer (BC) patients. The influence of both adaptive and innate immune responses on the therapeutic outcomes of HER2+BC patients has been extensively demonstrated.Long non-coding RNAs expressed in non-pathological complete response (pCR) HER2 positive BC ... [more]
J Immunother Cancer Oct. 01, 2022; 10(10); [Pubmed: 36252997]
Throughput
- High Throughput
Curated By
- BioGRID