BAIT

AGBL4

CCP6, RP11-342A17.1
ATP/GTP binding protein-like 4
GO Process (2)
GO Function (2)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

CCDC66

coiled-coil domain containing 66
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens

Proximity Label-MS

An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.

Publication

Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly.

Rodriguez-Calado S, Van Damme P, Aviles FX, Candiota AP, Tanco S, Lorenzo J

The cytosolic carboxypeptidase 6 (CCP6) catalyzes the deglutamylation of polyglutamate side chains, a post-translational modification that affects proteins such as tubulins or nucleosome assembly proteins. CCP6 is involved in several cell processes, such as spermatogenesis, antiviral activity, embryonic development, and pathologies like renal adenocarcinoma. In the present work, the cellular role of CCP6 has been assessed by BioID, a proximity ... [more]

Int J Mol Sci Jan. 09, 2023; 24(2); [Pubmed: 36674791]

Throughput

  • High Throughput

Additional Notes

  • BioID
  • FDR was set at 1%

Curated By

  • BioGRID