AQP1
Gene Ontology Biological Process
- ammonium transmembrane transport [IBA, ISO]
- ammonium transport [ISO, ISS]
- cGMP biosynthetic process [ISO, ISS]
- camera-type eye morphogenesis [ISO]
- carbon dioxide transmembrane transport [IBA, ISO, ISS]
- carbon dioxide transport [ISO, ISS]
- cation transmembrane transport [ISO]
- cell volume homeostasis [ISO, ISS]
- cellular homeostasis [ISO, ISS]
- cellular hyperosmotic response [ISO, ISS]
- cellular response to UV [ISO, ISS]
- cellular response to cAMP [ISO, ISS]
- cellular response to copper ion [ISO, ISS]
- cellular response to dexamethasone stimulus [ISO, ISS]
- cellular response to hydrogen peroxide [ISO, ISS]
- cellular response to hypoxia [ISO, ISS]
- cellular response to inorganic substance [ISO, ISS]
- cellular response to mechanical stimulus [ISO, ISS]
- cellular response to mercury ion [ISO, ISS]
- cellular response to nitric oxide [ISO]
- cellular response to retinoic acid [ISO, ISS]
- cellular response to salt stress [ISO, ISS]
- cellular water homeostasis [IBA]
- cerebrospinal fluid secretion [ISO]
- corticotropin secretion [ISO]
- establishment or maintenance of actin cytoskeleton polarity [ISO, ISS]
- glomerular filtration [ISO]
- glycerol transport [IDA, ISO]
- hyperosmotic response [IEP]
- hyperosmotic salinity response [IEP]
- lateral ventricle development [IEP, ISO]
- lipid digestion [ISO]
- maintenance of symbiont-containing vacuole by host [ISO, ISS]
- multicellular organismal water homeostasis [ISO]
- negative regulation of apoptotic process [ISO, ISS]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- nitric oxide transport [ISO, ISS]
- odontogenesis [ISO]
- pancreatic juice secretion [ISO]
- positive regulation of angiogenesis [ISO, ISS]
- positive regulation of cell migration [ISO]
- positive regulation of epithelial cell migration [IMP]
- positive regulation of fibroblast proliferation [ISO, ISS]
- positive regulation of lamellipodium assembly [IMP]
- positive regulation of saliva secretion [ISO, ISS]
- potassium ion transmembrane transport [ISO, ISS]
- potassium ion transport [ISO]
- renal water absorption [ISO]
- renal water transport [ISO, ISS]
- response to drug [ISO, ISS]
- response to estrogen [IEP]
- response to hormone [IEP]
- secretion by cell [ISO]
- secretory granule organization [ISO]
- sensory perception of pain [ISO]
- transepithelial water transport [ISO, ISS]
- water homeostasis [ISO]
- water transport [IMP, ISO]
- wound healing [ISO]
Gene Ontology Molecular Function- ammonium transmembrane transporter activity [IBA, ISO, ISS]
- carbon dioxide transmembrane transporter activity [IBA, ISO, ISS]
- ephrin receptor binding [ISO]
- glycerol channel activity [IBA]
- glycerol transmembrane transporter activity [IDA, ISO]
- intracellular cGMP activated cation channel activity [ISO, ISS]
- nitric oxide transmembrane transporter activity [ISO, ISS]
- potassium channel activity [ISO, ISS]
- potassium ion transmembrane transporter activity [ISO]
- protein binding [IPI]
- transmembrane transporter activity [ISO]
- water channel activity [IMP, ISO]
- water transmembrane transporter activity [ISO]
- ammonium transmembrane transporter activity [IBA, ISO, ISS]
- carbon dioxide transmembrane transporter activity [IBA, ISO, ISS]
- ephrin receptor binding [ISO]
- glycerol channel activity [IBA]
- glycerol transmembrane transporter activity [IDA, ISO]
- intracellular cGMP activated cation channel activity [ISO, ISS]
- nitric oxide transmembrane transporter activity [ISO, ISS]
- potassium channel activity [ISO, ISS]
- potassium ion transmembrane transporter activity [ISO]
- protein binding [IPI]
- transmembrane transporter activity [ISO]
- water channel activity [IMP, ISO]
- water transmembrane transporter activity [ISO]
Gene Ontology Cellular Component
- apical part of cell [ISO]
- apical plasma membrane [IDA, ISO]
- axon [ISO]
- axon terminus [IDA]
- basal plasma membrane [ISO, ISS]
- basolateral plasma membrane [IDA, ISO]
- brush border [IDA, ISO]
- brush border membrane [ISO, ISS]
- cell [ISO]
- cytoplasm [ISO, ISS]
- extracellular vesicular exosome [ISO]
- integral component of membrane [ISO]
- integral component of plasma membrane [IBA]
- membrane [ISO]
- neuron projection [IDA]
- neuronal cell body membrane [IDA]
- nuclear membrane [ISO, ISS]
- nucleus [ISO, ISS]
- plasma membrane [IDA, ISO]
- sarcolemma [ISO, ISS]
- symbiont-containing vacuole [ISO]
- symbiont-containing vacuole membrane [ISO]
MYH3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Aquaporin-1 translocation and degradation mediates the water transportation mechanism of acetazolamide.
Diuretic agents are widely used on the treatment of water retention related diseases, among which acetazolamide (AZA) acts originally as a carbonic anhydrase (CA) inhibitor. Aquaporin-1 (AQP1) being located in renal proximal tubules is required for urine concentration. Previously our lab has reported AZA putatively modulated AQP1. Aim of this study is to testify our hypothesis that regulating AQP1 may ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| AQP1 MYH3 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - | |
| MYH3 AQP1 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID