BAIT
USP48
RAP1GA1, USP31
ubiquitin specific peptidase 48
GO Process (3)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SSR1
TRAPA, PSEC0262
signal sequence receptor, alpha
GO Process (8)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- activation of signaling protein activity involved in unfolded protein response [TAS]
- cellular protein metabolic process [TAS]
- cotranslational protein targeting to membrane [TAS]
- endoplasmic reticulum unfolded protein response [TAS]
- gene expression [TAS]
- positive regulation of cell proliferation [TAS]
- translation [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
USP48 Stabilizes Gasdermin E to Promote Pyroptosis in Cancer.
Pyroptosis is a type of programmed cell death characterized by the activation of inflammatory caspases and the cleavage of gasdermin proteins. Pyroptosis can suppress tumor development and induce antitumor immunity, and activating pyroptosis is a potential treatment strategy for cancer. To uncover approaches to harness the anticancer effects of pyroptosis, we aimed to identify regulators of pyroptosis in cancer. A ... [more]
Cancer Res Apr. 04, 2023; 83(7);1074-1093 [Pubmed: 36607699]
Throughput
- High Throughput
Curated By
- BioGRID