BAIT
GABARAPL1
APG8-LIKE, APG8L, ATG8, ATG8B, ATG8L, GEC1
GABA(A) receptor-associated protein like 1
GO Process (4)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
FTH1
FHC, FTH, FTHL6, HFE5, PIG15, PLIF, OK/SW-cl.84
ferritin, heavy polypeptide 1
GO Process (8)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway.
Autophagy allows the degradation of cytosolic endogenous and exogenous material in the lysosome. Substrates are engulfed by double-membrane vesicles, coined autophagosomes, which subsequently fuse with lysosomes. Depending on the involvement of specific receptor proteins, autophagy occurs in a selective or nonselective manner. While this process is well understood at the level of bulky cargo such as mitochondria and bacteria, we ... [more]
Mol Cell Nov. 16, 2017; 68(4);786-796.e6 [Pubmed: 29149599]
Throughput
- High Throughput
Additional Notes
- High confidence interaction with a SILAC ratio > 1 in duplicate experiments.
Curated By
- BioGRID