BAIT
GABARAPL2
ATG8, ATG8C, GATE-16, GATE16, GEF-2, GEF2
GABA(A) receptor-associated protein-like 2
GO Process (9)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- autophagic vacuole assembly [IBA]
- autophagy [NAS]
- cellular response to nitrogen starvation [IBA]
- intra-Golgi vesicle-mediated transport [ISS]
- membrane fusion [IBA]
- mitochondrion degradation [IBA]
- negative regulation of proteasomal protein catabolic process [IMP]
- nucleophagy [IBA]
- positive regulation of ATPase activity [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ATP6V0D1
ATP6D, ATP6DV, P39, VATX, VMA6, VPATPD
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
GO Process (11)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
- activation of signaling protein activity involved in unfolded protein response [TAS]
- cellular iron ion homeostasis [TAS]
- cellular protein metabolic process [TAS]
- cilium assembly [ISS]
- endoplasmic reticulum unfolded protein response [TAS]
- insulin receptor signaling pathway [TAS]
- interaction with host [TAS]
- phagosome maturation [TAS]
- proton transport [NAS]
- transferrin transport [TAS]
- transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway.
Autophagy allows the degradation of cytosolic endogenous and exogenous material in the lysosome. Substrates are engulfed by double-membrane vesicles, coined autophagosomes, which subsequently fuse with lysosomes. Depending on the involvement of specific receptor proteins, autophagy occurs in a selective or nonselective manner. While this process is well understood at the level of bulky cargo such as mitochondria and bacteria, we ... [more]
Mol Cell Nov. 16, 2017; 68(4);786-796.e6 [Pubmed: 29149599]
Throughput
- High Throughput
Additional Notes
- High confidence interaction with a SILAC ratio > 1 in duplicate experiments.
Curated By
- BioGRID