BAIT

KTI12

SBBI81, TOT4, RP11-91A18.3
KTI12 homolog, chromatin associated (S. cerevisiae)
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

ELP2

SHINC-2, STATIP1, StIP
elongator acetyltransferase complex subunit 2
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Same but different - Molecular comparison of human KTI12 and PSTK.

Smejda M, Kadziolka D, Radczuk N, Krutyholowa R, Chramiec-Glabik A, Kedracka-Krok S, Jankowska U, Biela A, Glatt S

Kti12 and PSTK are closely related and highly similar proteins implicated in different aspects of tRNA metabolism. Kti12 has been identified as an essential regulatory factor of the Elongator complex, involved in the modification of uridine bases in eukaryotic tRNAs. PSTK phosphorylates the tRNASec-bound amino acid serine, which is required to synthesize selenocysteine. Kti12 and PSTK have previously been studied ... [more]

Biochim Biophys Acta Mol Cell Res Apr. 01, 2021; 1868(4);118945 [Pubmed: 33417976]

Throughput

  • High Throughput

Curated By

  • BioGRID