BAIT
KTI12
SBBI81, TOT4, RP11-91A18.3
KTI12 homolog, chromatin associated (S. cerevisiae)
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
ITSN1
ITSN, SH3D1A, SH3P17
intersectin 1 (SH3 domain protein)
GO Process (7)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- apoptotic signaling pathway [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of GTPase activity [NAS]
- positive regulation of apoptotic process [TAS]
- regulation of small GTPase mediated signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
- synaptic vesicle endocytosis [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Same but different - Molecular comparison of human KTI12 and PSTK.
Kti12 and PSTK are closely related and highly similar proteins implicated in different aspects of tRNA metabolism. Kti12 has been identified as an essential regulatory factor of the Elongator complex, involved in the modification of uridine bases in eukaryotic tRNAs. PSTK phosphorylates the tRNASec-bound amino acid serine, which is required to synthesize selenocysteine. Kti12 and PSTK have previously been studied ... [more]
Biochim Biophys Acta Mol Cell Res Apr. 01, 2021; 1868(4);118945 [Pubmed: 33417976]
Throughput
- High Throughput
Curated By
- BioGRID