BAIT

CDK2AP2

DOC-1R, p14
cyclin-dependent kinase 2 associated protein 2
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

MAP6

MTAP6, N-STOP, STOP
microtubule-associated protein 6
GO Process (2)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.

Spruijt CG, Graewe C, Kleinendorst SC, Baltissen MPA, Vermeulen M

The multi-subunit nucleosome remodeling and deacetylase (NuRD) complex consists of seven subunits, each of which comprises two or three paralogs in vertebrates. These paralogs define mutually exclusive and functionally distinct complexes. In addition, several proteins in the complex are multimeric, which complicates structural studies. Attempts to purify sufficient amounts of endogenous complex or recombinantly reconstitute the complex for structural studies ... [more]

FEBS J May. 01, 2021; 288(10);3231-3245 [Pubmed: 33283408]

Throughput

  • High Throughput

Curated By

  • BioGRID