BAIT

SRSF11

NET2, SFRS11, dJ677H15.2, p54, RP4-677H15.3
serine/arginine-rich splicing factor 11
Homo sapiens
PREY

HSPA12A

RP11-539I5.1
heat shock 70kDa protein 12A
GO Process (0)
GO Function (0)
GO Component (1)

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Publication

Alternative splicing of HSPA12A pre-RNA by SRSF11 contributes to metastasis potential of colorectal cancer.

Pan YJ, Huo FC, Kang MJ, Liu BW, Wu MD, Pei DS

Dysregulation of alternative splicing (AS) induced by serine/arginine-rich proteins has recently been linked to cancer metastasis. Nonetheless, as a member of the serine/arginine-rich protein family, the involvement of SRSF11 in colorectal cancer (CRC) is unknown.The TCGA dataset and clinical samples were used to assess SRSF11 expression levels in CRC. For SRSF11, functional experiments were conducted both in vitro and in ... [more]

Clin Transl Med Nov. 01, 2022; 12(11);e1113 [Pubmed: 36394206]

Throughput

  • Low Throughput

Curated By

  • BioGRID