BAIT

MOB3C

MOB1E, MOBKL2C
MOB kinase activator 3C
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

RBX1

BA554C12.1, RNF75, ROC1, RP11-554C12.1
ring-box 1, E3 ubiquitin protein ligase
UPS Project
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

Elkholi IE, Boulais J, Thibault MP, Phan HD, Robert A, Lai LB, Faubert D, Smith MJ, Gopalan V, Cote JF

Distinct functions mediated by members of the monopolar spindle-one-binder (MOB) family of proteins remain elusive beyond the evolutionarily conserved and well-established roles of MOB1 (MOB1A/B) in regulating tissue homeostasis within the Hippo pathway. Since MOB proteins are adaptors, understanding how they engage in protein-protein interactions, and help assemble complexes is essential to define the full scope of their biological functions. ... [more]

J Biol Chem Aug. 01, 2023; ();105123 [Pubmed: 37536630]

Throughput

  • High Throughput

Curated By

  • BioGRID