BAIT
NAB6
YML117W
Putative RNA-binding protein; associates with mRNAs encoding cell wall proteins in high-throughput studies; deletion mutants display increased sensitivity to some cell wall disrupting agents; expression negatively regulated by cAMP
GO Process (0)
GO Function (1)
GO Component (2)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Saccharomyces cerevisiae (S288c)
PREY
YDR524C-B
Putative protein of unknown function; YDR524C-B has a paralog, YCL048W-A, that arose from the whole genome duplication
GO Process (0)
GO Function (0)
GO Component (0)
Saccharomyces cerevisiae (S288c)
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
A posttranscriptional pathway regulates cell wall mRNA expression in budding yeast.
The fungal cell wall provides protection and structure and is an important target for antifungal compounds. A mitogen-activated protein (MAP) kinase cascade termed the cell wall integrity (CWI) pathway regulates transcriptional responses to cell wall damage. Here, we describe a posttranscriptional pathway that plays an important complementary role. We report that the RNA-binding proteins (RBPs) Mrn1 and Nab6 specifically target the ... [more]
Cell Rep Mar. 28, 2023; 42(3);112184 [Pubmed: 36862555]
Throughput
- High Throughput
Curated By
- BioGRID