BAIT

PPP1R14B

PHI-1, PLCB3N, PNG, SOM172
protein phosphatase 1, regulatory (inhibitor) subunit 14B
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

KRT6A

CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D, PC3
keratin 6A
GO Process (2)
GO Function (2)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Protein Phosphatase 1 Subunit PPP1R14B Stabilizes STMN1 to Promote Progression and Paclitaxel Resistance in Triple-Negative Breast Cancer.

Liao L, Zhang YL, Deng L, Chen C, Ma XY, Andriani L, Yang SY, Hu SY, Zhang FL, Shao ZM, Li DQ

Triple-negative breast cancer (TNBC) represents the most lethal subtype of breast cancer due to its aggressive clinical features and the lack of effective therapeutic targets. To identify novel approaches for targeting TNBC, we examined the role of protein phosphatases in TNBC progression and chemoresistance. Protein phosphatase 1 regulatory subunit 14B (PPP1R14B), a poorly defined member of the protein phosphatase 1 ... [more]

Cancer Res Feb. 03, 2023; 83(3);471-484 [Pubmed: 36484700]

Throughput

  • High Throughput

Curated By

  • BioGRID