BAIT
TGOLN2
TGN38, TGN46, TGN48, TGN51, TTGN2
trans-golgi network protein 2
GO Process (0)
GO Function (1)
GO Component (4)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LPL
HDLCQ11, LIPD
lipoprotein lipase
GO Process (14)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
- chylomicron remodeling [IC]
- fatty acid biosynthetic process [IC, IDA, ISS]
- lipoprotein metabolic process [TAS]
- phospholipid metabolic process [ISS]
- phototransduction, visible light [TAS]
- positive regulation of cholesterol storage [IMP]
- positive regulation of macrophage derived foam cell differentiation [IC]
- positive regulation of sequestering of triglyceride [IMP]
- retinoid metabolic process [TAS]
- small molecule metabolic process [TAS]
- triglyceride catabolic process [IDA, ISS]
- triglyceride homeostasis [IGI]
- triglyceride metabolic process [ISS]
- very-low-density lipoprotein particle remodeling [IDA, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.
Endosomal sorting maintains cellular homeostasis by recycling transmembrane proteins and associated proteins and lipids (termed "cargoes") from the endosomal network to multiple subcellular destinations, including retrograde traffic to the trans-Golgi network (TGN). Viral and bacterial pathogens subvert retrograde trafficking machinery to facilitate infectivity. Here, we develop a proteomic screen to identify retrograde cargo proteins of the endosomal SNX-BAR sorting complex ... [more]
Proc Natl Acad Sci U S A Jun. 21, 2022; 119(25);e2201980119 [Pubmed: 35696571]
Throughput
- High Throughput
Curated By
- BioGRID