BAIT
TGOLN2
TGN38, TGN46, TGN48, TGN51, TTGN2
trans-golgi network protein 2
GO Process (0)
GO Function (1)
GO Component (4)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PVRL2
CD112, HVEB, PRR2, PVRR2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
GO Process (16)
GO Function (5)
GO Component (7)
Gene Ontology Biological Process
- adherens junction organization [TAS]
- adhesion of symbiont to host [IDA]
- cell junction assembly [TAS]
- cell-cell junction organization [TAS]
- coreceptor-mediated virion attachment to host cell [IDA]
- fusion of virus membrane with host plasma membrane [IDA]
- homophilic cell adhesion via plasma membrane adhesion molecules [IDA]
- positive regulation of immunoglobulin mediated immune response [IMP]
- positive regulation of mast cell activation [IMP]
- positive regulation of natural killer cell mediated cytotoxicity [IMP]
- positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target [IMP]
- regulation of immune response [TAS]
- signal transduction [TAS]
- spermatid development [ISS]
- susceptibility to T cell mediated cytotoxicity [IDA]
- susceptibility to natural killer cell mediated cytotoxicity [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.
Endosomal sorting maintains cellular homeostasis by recycling transmembrane proteins and associated proteins and lipids (termed "cargoes") from the endosomal network to multiple subcellular destinations, including retrograde traffic to the trans-Golgi network (TGN). Viral and bacterial pathogens subvert retrograde trafficking machinery to facilitate infectivity. Here, we develop a proteomic screen to identify retrograde cargo proteins of the endosomal SNX-BAR sorting complex ... [more]
Proc Natl Acad Sci U S A Jun. 21, 2022; 119(25);e2201980119 [Pubmed: 35696571]
Throughput
- High Throughput
Curated By
- BioGRID