BAIT
TGOLN2
TGN38, TGN46, TGN48, TGN51, TTGN2
trans-golgi network protein 2
GO Process (0)
GO Function (1)
GO Component (4)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MEGF8
C19orf49, CRPT2, EGFL4, SBP1
multiple EGF-like-domains 8
GO Process (15)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- BMP signaling pathway [ISS]
- cell migration involved in gastrulation [IMP]
- craniofacial suture morphogenesis [IMP]
- determination of digestive tract left/right asymmetry [ISS]
- determination of heart left/right asymmetry [IMP]
- embryonic heart tube left/right pattern formation [ISS]
- embryonic heart tube morphogenesis [ISS]
- embryonic limb morphogenesis [ISS]
- embryonic skeletal system morphogenesis [ISS]
- epiboly involved in gastrulation with mouth forming second [IMP]
- fasciculation of sensory neuron axon [ISS]
- left/right pattern formation [IMP]
- limb morphogenesis [IMP]
- positive regulation of axon extension involved in axon guidance [ISS]
- regulation of gene expression [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.
Endosomal sorting maintains cellular homeostasis by recycling transmembrane proteins and associated proteins and lipids (termed "cargoes") from the endosomal network to multiple subcellular destinations, including retrograde traffic to the trans-Golgi network (TGN). Viral and bacterial pathogens subvert retrograde trafficking machinery to facilitate infectivity. Here, we develop a proteomic screen to identify retrograde cargo proteins of the endosomal SNX-BAR sorting complex ... [more]
Proc Natl Acad Sci U S A Jun. 21, 2022; 119(25);e2201980119 [Pubmed: 35696571]
Throughput
- High Throughput
Curated By
- BioGRID