PREY

HDLBP

HBP, PRO2900, VGL
high density lipoprotein binding protein
GO Process (0)
GO Function (3)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Publication

HDLBP-stabilized lncFAL inhibits ferroptosis vulnerability by diminishing Trim69-dependent FSP1 degradation in hepatocellular carcinoma.

Yuan J, Lv T, Yang J, Wu Z, Yan L, Yang J, Shi Y

Recent studies have suggested that exploring the potential mechanisms regulating ferroptosis vulnerability may contribute to improving the systemic therapeutic efficacy in HCC. High-density lipoprotein-binding protein (HDLBP), the largest RNA-binding protein, is an important transporter that protects cells from overaccumulation of cholesterol, but few studies have elucidated the role of HDLBP in the regulation of ferroptosis vulnerability in HCC. Our study ... [more]

Redox Biol Dec. 01, 2022; 58();102546 [Pubmed: 36423520]

Throughput

  • Low Throughput

Additional Notes

  • Bait is NONHSAG111059.1/lncFAL derived from PLXNB2 gene

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
HDLBP PLXNB2
Affinity Capture-RNA
Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Low-BioGRID
3565060

Curated By

  • BioGRID