BAIT
ATG16L1
APG16L, ATG16A, ATG16L, IBD10, WDR30, hCG_1817841
autophagy related 16-like 1 (S. cerevisiae)
GO Process (3)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SHROOM2
APXL, HSAPXL
shroom family member 2
GO Process (14)
GO Function (5)
GO Component (7)
Gene Ontology Biological Process
- actin filament bundle assembly [ISS]
- apical protein localization [ISS]
- brain development [ISS]
- camera-type eye development [ISS]
- camera-type eye morphogenesis [ISS]
- cell migration [ISS]
- cell morphogenesis [IDA, ISS]
- cellular pigment accumulation [ISS]
- ear development [ISS]
- establishment of melanosome localization [ISS]
- eye pigment granule organization [ISS]
- lens morphogenesis in camera-type eye [ISS]
- melanosome organization [ISS]
- sodium ion transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Pulse-SILAC and interactomics reveal distinct DDB1-CUL4 associated factors (DCAFs), cellular functions, and protein substrates.
Cullin-RING finger ligases (CRLs) represent the largest family of ubiquitin ligases. They are responsible for the ubiquitination of ?20% of cellular proteins degraded through the proteasome, by catalyzing the transfer of E2-loaded ubiquitin to a substrate. Seven Cullins are described in vertebrates. Among them, CUL4 associates with DDB1 to form the CUL4-DDB1 ubiquitin ligase complex, which is involved in protein ... [more]
Mol Cell Proteomics Sep. 07, 2023; ();100644 [Pubmed: 37689310]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID