BAIT
ATG16L1
APG16L, ATG16A, ATG16L, IBD10, WDR30, hCG_1817841
autophagy related 16-like 1 (S. cerevisiae)
GO Process (3)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SNX3
Grd19, MCOPS8, SDP3, RP3-429G5.4
sorting nexin 3
GO Process (12)
GO Function (6)
GO Component (11)
Gene Ontology Biological Process
- intralumenal vesicle formation [IMP]
- membrane invagination [IDA]
- negative regulation of early endosome to late endosome transport [IDA]
- negative regulation of phagocytosis [IMP]
- negative regulation of protein catabolic process [IDA]
- negative regulation of protein transport [IDA]
- negative regulation of viral entry into host cell [IDA]
- positive regulation of neuron projection development [ISS]
- protein to membrane docking [IDA]
- regulation of Wnt signaling pathway [IMP]
- response to bacterium [IDA]
- vesicle organization [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Pulse-SILAC and interactomics reveal distinct DDB1-CUL4 associated factors (DCAFs), cellular functions, and protein substrates.
Cullin-RING finger ligases (CRLs) represent the largest family of ubiquitin ligases. They are responsible for the ubiquitination of ?20% of cellular proteins degraded through the proteasome, by catalyzing the transfer of E2-loaded ubiquitin to a substrate. Seven Cullins are described in vertebrates. Among them, CUL4 associates with DDB1 to form the CUL4-DDB1 ubiquitin ligase complex, which is involved in protein ... [more]
Mol Cell Proteomics Sep. 07, 2023; ();100644 [Pubmed: 37689310]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID